[Pemphigus vulgaris - a case report].

Area of Science:

• Veterinary Dermatology
• Autoimmune Diseases
• Immunosuppressive Therapy

Background:

• Pemphigus vulgaris (PV) is a rare autoimmune blistering disease affecting the skin and mucous membranes.
• Standard treatment involves immunosuppressants, alone or in combination, based on disease severity.
• This report details a canine case of PV, including diagnosis and long-term management.

Purpose of the Study:

• To present a case study of pemphigus vulgaris in a dog.
• To review current literature on PV treatment.
• To document the diagnostic process and successful long-term management of canine PV.

Main Methods:

• Clinical examination of a 9-year-old male dog with suspected autoimmune dermatosis.
• Histopathological examination of skin and mucosal biopsies.
• Implementation and monitoring of long-term immunosuppressive therapy (Prednisolone, Azathioprine).

Main Results:

• The dog presented with characteristic mucocutaneous lesions, including vesicles and ulcerations.
• Histopathology confirmed the diagnosis of pemphigus vulgaris.
• The dog achieved complete remission with sustained immunosuppressive treatment.

Conclusions:

• Pemphigus vulgaris can occur in young dogs and presents with distinct clinical signs.
• A combination of Prednisolone and Azathioprine is an effective long-term treatment strategy.
• Early diagnosis and consistent immunosuppressive therapy are crucial for successful management of canine PV.