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Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

396
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
396

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Related Experiment Video

Updated: Jan 15, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
06:04

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

506

Alternative Access for TAVR: A State-of-the-Art Review and Practical Guide.

Hans-Josef Feistritzer1, Oliver Dumpies1, Liesbeth Rosseel2

  • 1Heart Center Leipzig, University of Leipzig, Leipzig, Germany.

JACC. Cardiovascular Interventions
|October 15, 2025
PubMed
Summary
This summary is machine-generated.

Transcatheter aortic valve replacement (TAVR) guidelines focus on transfemoral (TF) access. This review explores alternative access routes when TF is not feasible, aiding TAVR procedure planning.

Keywords:
TAVRalternative accesstransaxillarytranscarotidtranscavaltransthoracic

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Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Vascular Surgery

Background:

  • Current guidelines for transcatheter aortic valve replacement (TAVR) primarily recommend transfemoral (TF) access.
  • Advances in technology and technique have expanded TF access suitability, but its limits in complex anatomies are debated.
  • Alternative transvascular routes are increasingly used for TAVR when TF access is not optimal, yet the best approach is unclear.

Purpose of the Study:

  • To review alternative access strategies for TAVR.
  • To discuss the decision-making process for choosing between TF and non-TF access.
  • To outline key considerations for selecting and executing alternative TAVR access sites.

Main Methods:

  • State-of-the-art review of current literature and practices.
  • Analysis of decision-making algorithms for TAVR access.
  • Discussion of alternative access site selection and procedural techniques.

Main Results:

  • TF access is the preferred TAVR route, but its feasibility has limitations.
  • Alternative transvascular access routes are viable options for select TAVR patients.
  • Optimal selection and execution of alternative access are crucial for TAVR success.

Conclusions:

  • Determining the threshold for TF access feasibility in TAVR is critical.
  • Alternative access site selection requires careful consideration of patient anatomy and procedural factors.
  • This review provides guidance on optimizing non-TF access for TAVR procedures.