Anemia of Prematurity in an ELBW Neonate of Jehovah's Witness Parents

Lauren M McCotter1, Amy J Jnah2

  • 1Department of Advanced Practice Nursing Practice and Education, East Carolina University College of Nursing, Greenville, NC, USA mccotterl22@students.ecu.edu.

Neonatal Network : NN
|October 15, 2025
PubMed

Insights

Anemia of prematurity affects premature infants due to decreased red blood cell mass. This case highlights ethical dilemmas when Jehovah

Area of Science:

  • Neonatal Medicine
  • Pediatric Hematology

Background:

  • Anemia of prematurity is a common complication in preterm infants, linked to gestational age and medical interventions.
  • Severity correlates with gestational age, comorbidities affecting erythropoiesis, and frequent blood draws.
  • Blood transfusions are standard treatment but raise ethical concerns for specific religious groups.

Purpose of the Study:

  • To present a case study of anemia of prematurity in an infant born to Jehovah's Witness parents.
  • To discuss the pathophysiology and clinical presentation of anemia in preterm infants.
  • To explore the ethical and legal challenges faced by healthcare providers when families refuse life-saving blood transfusions.

Main Methods:

  • Case study of a 24-week gestation infant.
  • Review of the pathophysiology of anemia of prematurity.
  • Discussion of clinical manifestations and management considerations.

Main Results:

  • The case involved a preterm infant with anemia of prematurity whose parents, adhering to Jehovah's Witness beliefs, refused blood transfusions.
  • The study details the infant's condition, emphasizing the challenges in managing anemia in this context.
  • Pathophysiology and clinical signs of anemia in premature infants are described.

Conclusions:

  • Managing anemia of prematurity in infants of parents with religious objections to blood transfusions presents significant ethical and legal challenges.
  • Healthcare providers must navigate complex decisions balancing infant well-being with parental rights and beliefs.
  • Further discussion and guidelines are needed for such complex ethical scenarios in neonatal care.

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