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Updated: Jan 15, 2026
Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management
Published on: February 28, 2025
[Research advances in three-dimensional bioprinted wound dressings]
Chenghai Shi1, Changbin Lei1, Lingxiao He1
1Trauma Center, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu Sichuan, 610041, P. R. China.
Objective:
To review the research progress of three-dimensional (3D) bioprinting technology for wound dressing design and preparation.
Methods:
The literature on 3D bioprinted wound dressings in recent years, both domestically and internationally, was retrieved. The core principles of 3D bioprinting technology, mainstream methods, and their applications in wound dressings design and preparation were summarized.
Results:
By leveraging precise spatial manipulation capabilities and multi-material integration, 3D bioprinting technology constructs the functionalized wound dressings with complex structures and bioactivity. These dressings primarily function across several dimensions: wound hemostasis, infection control, controlled drug release, and monitoring wound healing.
Conclusion:
Although 3D bioprinted wound dressings can promote wound healing through multiple dimensions, large-scale clinical validation is still lacking. Future efforts should further clarify their clinical value and scope of application to provide more efficient, precise, and patient-comfortable treatment options for refractory wounds .
