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Improved Survival with Improved NAPRC Compliance: A Single-Institution Experience
Harry Wasvary1, Jacob A Applegarth1, Scarlett Hao1
1Corewell Health William Beaumont University Hospital, Royal Oak, MI 48073, USA.
Journal of Clinical Medicine
|October 16, 2025
Summary
Compliance with National Accreditation Program for Rectal Cancer (NAPRC) standards significantly improves rectal cancer patient survival. Adhering to at least eight NAPRC standards offers a survival benefit three years post-diagnosis.
Area of Science:
- Oncology
- Surgical Quality Improvement
Background:
- The National Accreditation Program for Rectal Cancer (NAPRC) was established in 2017 to standardize rectal cancer care.
- This study evaluates the impact of NAPRC standards adherence on patient survival outcomes.
Purpose of the Study:
- To determine the association between compliance with NAPRC standards and three-year survival rates in rectal cancer patients.
- To quantify the survival benefit conferred by adherence to NAPRC guidelines.
Main Methods:
- A prospective database collected data on compliance with 15 NAPRC standards for patients diagnosed between August 2019 and August 2021.
- Retrospective analysis of this database assessed compliance levels and three-year survival post-diagnosis.
Main Results:
- Patients were categorized into low, moderate, and high compliance groups, with no significant differences in age, sex, race, or disease stage.
- Both moderate and high compliance groups demonstrated statistically significant reductions in hazard ratios compared to the low compliance group (HR 0.22 and HR 0.12, respectively).
Conclusions:
- Increased adherence to NAPRC standards is directly correlated with improved survival outcomes for rectal cancer patients.
- Rectal cancer patients receiving care aligned with at least eight NAPRC standards experienced a significant three-year survival advantage.
