Related Experiment Video
Updated: Jan 15, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Patients Who Refuse Blood Transfusions Should Not Be Discouraged from Immediate Direct-to-Implant Breast
Maria Skonieczna1, Piotr Strzałka2,3, Marek Zadrożny1
1Department of Surgical Oncology and Breast Diseases, Polish Mother's Memorial Hospital-Research Institute, 93-338 Lodz, Poland.
Mastectomy with direct-to-implant breast reconstruction (M-DTI) is safe for patients avoiding blood transfusions. This study found no increased bleeding risk, making M-DTI a viable option for bloodless medicine needs.
Area of Science:
- Oncology
- Plastic Surgery
- Surgical Outcomes
Background:
- Direct-to-implant (DTI) breast reconstruction is a common immediate breast restoration method post-mastectomy.
- DTI reconstruction improves quality of life without compromising oncological outcomes.
- Its safety in patients refusing blood transfusions is not well-established.
Purpose of the Study:
- To evaluate the safety of mastectomy with direct-to-implant breast reconstruction (M-DTI) in terms of bleeding complications.
- To compare bleeding risks between mastectomy alone (MA) and M-DTI.
Main Methods:
- Retrospective review of 490 patients undergoing MA or M-DTI from January 2021 to June 2023.
- Analysis of patient demographics, surgical details, and bleeding complication rates.
- Comparison of complication rates between the two surgical groups.
Main Results:
- Bleeding complications occurred in 2.4% of MA patients and 1.8% of M-DTI patients (p=0.249).
- No significant difference in bleeding risk was observed between MA and M-DTI.
- Severe bleeding risk was independent of patient age, diagnosis, or procedure type.
Conclusions:
- Immediate breast reconstruction following mastectomy does not elevate bleeding risks.
- Mastectomy with direct-to-implant reconstruction is a safe and viable option for patients requiring bloodless medicine.
- This approach supports patient choice and quality of life without compromising safety.
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