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Updated: Jan 15, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
Published on: December 1, 2013
A Rare Case of Metastatic Breast Cancer in the Bladder
Lydia My Chang1,2, Parthvi Vanalia3, Adam Jones2
1Core Surgical Training, Health Education England North West Deanery, Northwest, GBR.
Abstract:
This case describes the rare occurrence of breast cancer with metastasis to the bladder. This woman in her 60s, was first diagnosed with breast cancer in the mid-2000s. Nearly 20 years later, she developed recurrence at her primary site and metastasis to the skin and bones, and subsequently to the bladder. The involvement of the bladder initially presented as a stage 3 acute kidney injury during routine blood tests whilst the patient was undergoing chemotherapy for local breast cancer recurrence and metastasis. Initial ultrasound imaging showed bilateral hydroureteronephrosis. Subsequent computed tomography (CT) scan with contrast revealed a thickened bladder wall in addition to the bilateral hydroureteronephrosis. She underwent bilateral nephrostomy insertions under local anaesthesia as an emergency, and a flexible cystoscopy, which revealed a tumour in the bladder. This patient then underwent a transurethral resection of bladder tumour (TURBT) and histology samples from this resection revealed metastatic breast cancer in the bladder rather than a primary tumour from the bladder.

