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Association between the C-reactive protein-albumin-lymphocyte (CALLY) index and mortality in elderly patients with
Hui Shen1,2, Tonghu Jin2, Qing Mei3
1Cerebrovascular Disease Department, Neurological Disease Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Background:
While the novel C-reactive protein-albumin-lymphocyte (CALLY) index-integrating inflammatory, nutritional, and immune markers-has proven valuable for prognosis in various diseases, its utility in predicting outcomes for dysphagia patients is still unclear.
Methods:
This retrospective cohort analysis utilized data sourced from the Dryad Digital Repository. The CALLY index (albumin × lymphocyte count/C-reactive protein × 104) was calculated. After logarithmic transformation (Ln-CALLY), the patients were divided into low Ln-CALLY group (≤ 2.21) and high Ln-CALLY group (>2.21). All-cause mortality served as the primary endpoint. The association between Ln-CALLY and outcomes was evaluated using Kaplan-Meier analysis with log-rank testing and multivariable Cox proportional hazards regression. The dose-response relationship was evaluated by restricted cubic splines (RCS).
Results:
This study enrolled 253 elderly dysphagia patients. Analysis revealed Ln-CALLY as a significant predictor of all-cause mortality.
Conclusion:
The CALLY index shows promise as a predictor of mortality risk and long-term outcomes in older dysphagia patients.
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