Medication, Nutrition, and Hygiene in COVID-19 Prevention and Treatment: A Comprehensive Narrative Review
1De-An Clinic Tainan City 711 Taiwan.
Abstract:
Despite advances in Coronavirus Disease 2019 (COVID-19) prevention and treatment, emerging variants and persistent challenges continue to affect global health. Studies are retrieved from PubMed using title-based searches for COVID-19, SARS-CoV-2, and related therapies from 2020 to 2025, focusing on randomized controlled trials, systematic reviews, and clinical guidelines. This review explores treatments, nutrients, and adjuvant therapies that support the immune system in fighting COVID-19. It highlights the role of antiviral medications such as remdesivir, nirmatrelvir/ritonavir, and molnupiravir in reducing mortality and hospitalizations. Additionally, adjunctive therapies like corticosteroids, interleukin-6 (IL-6) inhibitors, Janus kinase (JAK) inhibitors, and N-acetylcysteine (NAC) are discussed for their potential to modulate inflammation. Nutritional support, including omega-3 fatty acids, vitamins D, C, and A, zinc, selenium, and probiotics, enhances immune function. Preventive measures, such as hygiene practices, wearing masks, and physical distancing, reduce transmission. An integrated approach that combines antiviral treatments with adjunctive therapies, prevention, and nutrition is crucial for improving outcomes.
Insights
This review highlights effective COVID-19 treatments, including antivirals and immune-supporting nutrients. An integrated approach combining therapies, prevention, and nutrition is key to improving outcomes against Coronavirus Disease 2019.
Area of Science:
- * Infectious Diseases and Virology
- * Immunology and Nutritional Science
Background:
- * Coronavirus Disease 2019 (COVID-19) continues to pose global health challenges despite advancements.
- * Emerging variants necessitate ongoing research into effective prevention and treatment strategies.
Purpose of the Study:
- * To review current treatments, nutritional support, and adjuvant therapies for COVID-19.
- * To explore strategies for enhancing immune function and modulating inflammation in COVID-19 patients.
Main Methods:
- * Literature search of PubMed for studies on COVID-19 and related therapies (2020-2025).
- * Focus on randomized controlled trials, systematic reviews, and clinical guidelines.
- * Analysis of antiviral medications, adjunctive therapies, and nutritional interventions.
Main Results:
- * Antiviral medications (remdesivir, nirmatrelvir/ritonavir, molnupiravir) reduce mortality and hospitalizations.
- * Adjunctive therapies (corticosteroids, IL-6 inhibitors, JAK inhibitors, NAC) modulate inflammation.
- * Nutritional support (omega-3s, vitamins D, C, A, zinc, selenium, probiotics) enhances immune function.
- * Preventive measures (hygiene, masks, distancing) reduce transmission.
Conclusions:
- * An integrated approach combining antivirals, adjunctive therapies, prevention, and nutrition is crucial for managing COVID-19.
- * Optimizing immune response and reducing inflammation are key therapeutic goals.
- * Continued research and adherence to public health measures are vital.
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