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Updated: Jan 15, 2026

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Surgical Technique for the Implantation of Tissue Engineered Vascular Grafts and Subsequent In Vivo Monitoring
Published on: April 3, 2015
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T-NEXT graft: step by step operative technique.
Marco Di Eusanio1, Paolo Berretta1, Emanuele Gatta2
1Cardiac Surgery Unit, Lancisi Cardiovascular Center, Polytechnic University of Marche, Ancona, Italy.
Annals of Cardiothoracic Surgery
|October 16, 2025
Summary
The T-NEXT graft offers improved lifetime management for complex aortic arch disease. Its design facilitates future reoperations and endovascular access, addressing limitations of the frozen elephant trunk (FET) technique.
Area of Science:
- Cardiovascular Surgery
- Vascular Surgery
- Medical Device Innovation
Background:
- The frozen elephant trunk (FET) technique is standard for complex aortic arch disease.
- Reinterventions are common due to graft design limitations, especially with proximal anastomoses.
- Conventional FET grafts may impede future proximal reoperations and distal endovascular access.

