RadioPharm: the database of radiopharmaceuticals

Radiopharmaceuticals (RPs) have emerged as a promising group of therapeutic/diagnostic agents with tremendous pharmaceutical advantages and profitable market value. With the rapid advances in this direction, there is an increasing demand for a knowledge base providing RP-relevant data. However, no such database has been available yet. Herein, a database RadioPharm was therefore developed to depict the pharmaceutical data for 3141 RPs and the radioactive characteristics for the nuclide in each RP. Particularly, our RadioPharm is unique in (i) providing the largest number of RPs (including 68 approved, 575 in clinical trials, and 2498 investigative RPs) among the existing databases, (ii) offering the comprehensive radioactive characteristics for the radionuclide in each RP, and (iii) implementing a multidirectional approach for data retrieval (from diverse perspectives of RP, radionuclide, target, and indication). Because of the important role of all those accumulated data in radiopharmaceutical research, RadioPharm is expected to attract broad interest from research community, which is now fully accessible by all users at https://idrblab.org/radiopharm/.