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Patterns for End-of-Life Care of Patients With Advanced Cancer: An Integrative Review.
Camelia Ancuta1,2, Sandra Martins Pereira3, Liliana Rogozea1
1University of Transilvania, Brasov, Romania.
American Journal of Therapeutics
|October 16, 2025
Summary
End-of-life care for advanced cancer patients varies significantly. Comfort-oriented care, often involving palliative teams, improves outcomes, while non-comfort-oriented care in hospitals can lead to distress.
Area of Science:
- Palliative Care
- Oncology
- End-of-Life Studies
Background:
- End-of-life care for advanced cancer patients is crucial for dignity.
- Care can be comfort-oriented or non-comfort-oriented, impacting quality of life.
- Existing end-of-life care patterns for advanced cancer patients require clarification.
Purpose of the Study:
- To provide a comprehensive overview of end-of-life care patterns in advanced cancer patients.
- To identify factors associated with comfort-oriented versus non-comfort-oriented care.
- To inform strategies for improving patient-centered end-of-life care.
Main Methods:
- Integrative review using Whittemore's method.
- Searches conducted in PubMed, Science Direct, Scopus, and Google Scholar.
- Population/Patient, Exposure, and Outcome (PEO) format used for research question.
Main Results:
- Twenty-four articles were reviewed, analyzing care settings, palliative care involvement, intervention intensity, duration, and advance planning.
- Comfort-oriented care was exclusively in community settings; hospitals offered both.
- Palliative care involvement correlated with comfort-oriented care, earlier recognition of dying, and optimized medication.
Conclusions:
- New strategies are needed to guide clinical practice for end-of-life care.
- Ensuring patient-centered care is paramount.
- Distinguishing and promoting comfort-oriented care pathways is essential.
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