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Updated: Jan 6, 2026

Dissection and Culture of Mouse Embryonic Kidney
Published on: May 17, 2017
Eph-ephrin signaling and its potential role in female reproductive tract development
1Division of Genetics, Department of Pediatrics, American Family Children´s Hospital, University of Wisconsin-Madison, 1500 Highland Ave Madison, Madison, WI, 53705, USA. pprasun@wisc.edu.
Abstract:
Eph-ephrin signaling plays crucial role in the development of nervous and cardiovascular system. Its role in female reproductive system development is unknown. Clinical observations in a rare developmental disorder, Craniofrontonasal syndrome, underscores the potential role of Eph-ephrin signaling in the development of female reproductive tract. In this minireview, the basics of Eph-ephrin signaling and its known role in development have been discussed. Putative role of Eph-ephrin in female reproductive tract development is discussed based on the available clinical evidence and animal studies.
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