Related Experiment Video
Updated: Jun 20, 2026

10:42
A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
Published on: January 28, 2020
6.9K
Soft Tissue Asymmetry in Patients With Cleft Lip and Palate Using Stereoscopic Photography
Lijuan Zhou1,2, Yang Cao3, Guangxu Sun2,4
1Department of Orthodontics, Tianjin Stomatological Hospital, School of Medicine, Nankai University, Tianjin.
The Journal of Craniofacial Surgery
|October 16, 2025
Summary
Patients with cleft lip and palate, including unilateral cleft lip with alveolar cleft (UCLA) and unilateral complete cleft lip and palate (UCLP), exhibit significant facial soft tissue asymmetry. UCLP patients show more severe and widespread deformities than UCLA patients.
Area of Science:
- Craniofacial surgery
- Plastic surgery
- Medical imaging
Background:
- Unilateral cleft lip and palate conditions cause significant facial asymmetry.
- Long-term soft tissue deformities require thorough evaluation for effective treatment planning.
Purpose of the Study:
- To assess and compare long-term facial soft tissue asymmetry in patients with unilateral cleft lip with alveolar cleft (UCLA) and unilateral complete cleft lip and palate (UCLP).
Main Methods:
- Utilized 3D photography (3dMD) to create digital models of 21 UCLA and 18 UCLP patients.
- Analyzed bilateral facial symmetry indices using paired t-tests.
- Performed mirror image analysis to determine asymmetry distribution and severity.
Main Results:
- Both UCLA and UCLP groups displayed significant differences in nostril, nasal alar, and upper lip measurements.
- UCLA patients showed mild asymmetry primarily in the ala, nostril, and cheilion.
- UCLP patients exhibited severe asymmetry affecting the entire midface.
Conclusions:
- 3D analysis confirms facial soft tissue deformities, particularly in the nasolabial area, for both UCLA and UCLP patients.
- UCLP patients present with greater and more extensive facial asymmetry compared to UCLA patients.
- Further interventions are necessary to address and improve facial malformations in both clefting types.

