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Updated: Jul 27, 2026

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
Published on: January 11, 2020
Morphological MRI knee phantoms: Design, preliminary results, and perspectives for applied research
H Yusuff1, T Willaume2, E Breton1
1Université de Strasbourg, CNRS, Inserm, ICube UMR 7357, Strasbourg, France.
Introduction:
There is currently no MRI phantom capable of generating high-precision anatomical images in musculoskeletal (MSK) imaging. Yet, such phantoms, also referred to as "super-phantoms", could offer substantial value for MRI sequence testing, optimization, and applied research.
Methods:
In this study, we focused on the knee region, creating phantoms based on reference MRI slices. Using computer-aided design (CAD) software, detailed anatomical structures were modeled, 3D printed, and filled with tissue-mimicking gels. MRI acquisitions were then performed to evaluate the potential of these tools.
Results:
The resulting images demonstrated high anatomical fidelity and clinically realistic MRI-weighted contrasts. These phantoms show promise for a range of applications, including training, sequence optimization, hardware evaluation, and ethical aspects.
Conclusion:
Although technical refinements are needed to improve long-term stability and achieve more accurate relaxometry, the phantoms hold strong potential for supporting applied MRI research.
Implication For Practice:
This new type of phantom can be considered an original and versatile tool for sequence development and hardware comparison. Moreover, it represents a valuable means to promote evidence-based practices and encourage MRI professionals (e.g. radiographers) to engage in applied research initiatives.
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