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Author Spotlight: Implementing the Enhanced Recovery After Surgery Concept in Rehabilitation Following Anterior Cruciate Ligament Reconstruction
Published on: March 1, 2024
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Predictors of 2-Year PROMIS Physical Function After Primary ACL Reconstruction
Sara Jain1, Michael A McCurdy1, Leah E Henry1
1Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, Maryland, United States.
The Journal of Knee Surgery
|October 16, 2025
Summary
Younger age, higher income, and better baseline PROMIS Fatigue predict better physical function 2 years after anterior cruciate ligament reconstruction (ACLR). These factors also predict greater improvement in physical function post-ACLR, aiding preoperative patient counseling.
Area of Science:
- Orthopaedic Surgery
- Rehabilitation Medicine
- Patient-Reported Outcomes
Background:
- Patient-Reported Outcomes Measurement Information System (PROMIS) is crucial for assessing outcomes post-surgery.
- Previous studies explored PROMIS physical function (PF) predictors after general knee surgery.
- PROMIS PF 2 years after anterior cruciate ligament reconstruction (ACLR) requires further investigation.
Purpose of the Study:
- To identify predictors of 2-year PROMIS PF after primary ACLR.
- To investigate factors associated with 2-year PROMIS PF and its improvement post-ACLR.
Main Methods:
- Prospective orthopaedic registry data from 2015-2018.
- Analysis of 141 patients completing 2-year follow-up surveys after primary ACLR.
- Bivariate and multivariate regression analyses of baseline characteristics and PROs.
Main Results:
- Younger age, lower BMI, student status, and lower comorbidity index predicted better 2-year PROMIS PF.
- Higher income and private insurance predicted greater improvement in PROMIS PF.
- Younger age, higher income, and better baseline PROMIS Fatigue independently predicted 2-year PROMIS PF and its improvement.
Conclusions:
- Age, income, and baseline PROMIS Fatigue are key predictors of 2-year physical function outcomes after ACLR.
- These nonmodifiable factors can inform preoperative patient counseling regarding recovery expectations.

