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Related Concept Videos

Knee Joint01:23

Knee Joint

3.4K
The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
3.4K

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The Effect of Preoperative Symptom Duration on 10-Year Outcomes After Hip Arthroscopy for Femoroacetabular Impingement Syndrome: A Matched Analysis.

The American journal of sports medicine·2026
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Increased Posterior Tibial Slope Correlates With Greater Odds of Reoperation and Failure After Meniscal Allograft Transplantation.

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Lower Rates of Osteoarthritis Progression and Improved Knee Stability Are Observed With the Double-Bundle Versus Single-Bundle Posterior Cruciate Ligament Reconstruction Technique: A Systematic Review.

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Outcomes Following Multiligament Knee Injuries: A Systematic Review of Studies With a Minimum 7-Year Follow-up.

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Clinical Outcomes of Unipolar Versus Bipolar Patellofemoral Fresh Osteochondral Allograft Transplantation.

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Editorial Commentary: Is High Tibial Osteotomy All We Need? No Differences in Patient-Reported Outcomes in Medial Meniscal Posterior Root Tears With Varus Deformity Between Isolated High Tibial Osteotomy and Osteotomy With Meniscal Centralization and All-Inside Root Repair.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·2026

Related Experiment Video

Updated: May 6, 2026

Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus
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Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus

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Orthobiologics for Meniscus Injuries.

Juan Bernardo Villarreal-Espinosa1, Fernando Gomez-Verdejo1, Andrew S Bi1

  • 1Department of Orthopaedics, Rush University Medical Center, 1620 W Harrison St, Chicago, IL, 60612, USA.

Clinics in Sports Medicine
|October 16, 2025
PubMed
Summary

Biologic treatments for meniscal tears aim to boost healing using growth factors and regenerative cells. However, clinical evidence is inconsistent, requiring further research to establish their routine use.

Keywords:
BMACMeniscal repairMeniscusOrthobiologicsPlatelet-rich plasmaStem cells

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Area of Science:

  • Orthopedic surgery
  • Regenerative medicine
  • Biologic therapies

Background:

  • Meniscal tears are common knee injuries.
  • Current treatments have limitations.
  • Biologic enhancement offers a potential new approach.

Purpose of the Study:

  • To evaluate the efficacy of biologic enhancement for meniscal tears.
  • To explore the use of growth factors and regenerative cells in meniscal healing.

Main Methods:

  • Review of preclinical and clinical studies.
  • Analysis of growth factor and regenerative cell upregulation.
  • Assessment of healing outcomes.

Main Results:

  • Preclinical studies show promising results.
  • Clinical outcomes are mixed and inconclusive.
  • Further investigation is warranted.

Conclusions:

  • Biologic enhancement shows potential but requires more research.
  • Efficacy as a routine treatment strategy is not yet confirmed.
  • Prospective studies with longer follow-up are needed.