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Development of a Novel Frailty Trigger for Use at Triage in the Emergency Department
Elizabeth Moloney1,2, Mark R O'Donovan2, Dearbhla Burke3
1Department of Geriatric Medicine, Mercy University Hospital, Cork City, Ireland.
Insights
The Frailty Trigger accurately identifies frail older adults in the Emergency Department (ED), predicting longer hospital stays and reduced survival. This tool aids in appropriate triage for vulnerable elderly patients.
Area of Science:
- Geriatric Medicine
- Emergency Medicine
- Health Services Research
Background:
- Emergency Department (ED) triage often misses frailty in older adults, leading to potential under-prioritization.
- International guidelines recommend frailty assessment in triage, but adoption is limited.
Purpose of the Study:
- To develop and evaluate a novel "Frailty Trigger" for identifying frailty in older adults during ED triage.
- To assess the diagnostic accuracy and clinical utility of the Frailty Trigger compared to existing tools.
Main Methods:
- A Frailty Trigger was developed using systematic review and eDelphi. Diagnostic accuracy was tested in 313 adults aged ≥70 in an ED, comparing it to CFS, VIP, and PRISMA-7 against a comprehensive geriatric assessment (CGA).
- Key metrics included diagnostic accuracy (AUC), administrative time, length of stay (LOS), and 1-year mortality.
Main Results:
- The Frailty Trigger demonstrated excellent diagnostic accuracy (AUC 0.822), comparable to VIP and other measures, with a mean administrative time of 25.5 seconds.
- Positive Frailty Trigger scores correlated with significantly increased LOS (6.4 vs 2.3 days) and reduced 1-year survival (HR 2.2).
Conclusions:
- The Frailty Trigger is a rapid and accurate tool for identifying frailty in the ED setting.
- Its application in triage can predict adverse outcomes like prolonged LOS and mortality, warranting further study on implementation and impact on patient pathways.
Background:
Emergency Department (ED) Triage identifies patients with urgent needs. Frailty is not routinely identified and older patients presenting atypically may be inappropriately triaged as low priority. The introduction of a frailty modifier at triage is recommended in international guidelines, but is not yet widely-adopted.
Methods:
A Frailty Trigger was developed following a systematic review and two-round eDelphi. To investigate diagnostic test accuracy for frailty, we recruited consecutive adults aged ≥ 70 attending a university hospital ED between December 2021 and February 2022, comparing the Trigger to the Clinical Frailty Scale (CFS), Variable indicative of Placement (VIP), and PRISMA-7. An independent comprehensive geriatric assessment (CGA) determined frailty status.
Results:
In total, 313 adults aged ≥ 70 years were available, median age 78 ± 9 years and 46% were female. Half (51%) were frail based on the CGA. The Frailty Trigger had excellent diagnostic accuracy for frailty, Area Under the Curve (AUC) of 0.822, 95% confidence interval (CI): 0.780-0.865, similar to the VIP (AUC 0.820, p = 0.937), although significantly lower than the PRISMA-7 (AUC 0.896) and CFS (AUC 0.946). Mean administrative time was 25.5 s (SD ±10.9 s). Scoring positive on the Frailty Trigger was associated with increased length of stay (LOS), median 6.4 versus 2.3 days (p < 0.001). After adjustment for age, sex, and co-morbidity, a positive score was associated with reduced survival at 1 year (Hazard Ratio 2.2; 95% CI 1.15-4.33, p = 0.017).
Conclusion:
When applied as part of ED triage, the Frailty Trigger showed excellent diagnostic accuracy for frailty when compared to validated screens and was quick to use. It predicted LOS and mortality. Studies are required to examine feasibility and its effect on frailty pathways from triage.
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