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Related Concept Videos

Endocrine Signaling01:45

Endocrine Signaling

67.8K
Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
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The Endocrine System01:29

The Endocrine System

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The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that...
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Chemical Signaling in the Endocrine System01:08

Chemical Signaling in the Endocrine System

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A signaling cascade is a series of events that facilitates the transmission of information within or between cells, culminating in a targeted response in the recipient cell. As chemical messengers, hormones are pivotal in initiating and modulating these intricate signaling cascades based on their solubility.
Lipid-soluble hormones, such as steroid hormones, demonstrate an intracellular action. These hormones traverse cell membranes due to their lipid nature. Once inside the target cell, they...
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What is the Endocrine System?00:46

What is the Endocrine System?

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The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
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An Overview of the Endocrine System01:10

An Overview of the Endocrine System

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The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
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Structures of the Endocrine System00:59

Structures of the Endocrine System

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The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
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EndoCompass project: environmental endocrinology.

Anna-Maria Andersson1, Stefano Cianfarani2,3,4, Josef Köhrle5

  • 1Department of Growth and Reproduction and International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, 2100 Copenhagen, Denmark.

European Journal of Endocrinology
|October 17, 2025
PubMed
Summary
This summary is machine-generated.

Environmental factors significantly disrupt endocrine systems, impacting hormone health. Strategic research is crucial to address endocrine-disrupting chemicals (EDCs) and pollution for better public health policy.

Keywords:
EDCEndoCompassenvironmentroadmap

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Area of Science:

  • Environmental endocrinology
  • Endocrine disruptors
  • Hormone health

Background:

  • Endocrine science is underrepresented in EU research despite hormone health's importance.
  • A gap exists between endocrine disorder impact and research prioritization.
  • The EndoCompass project aims to define strategic research priorities in endocrinology.

Purpose of the Study:

  • Identify and promote strategic research priorities in endocrine science.
  • Address critical hormone-related health challenges.
  • Align research funding with high-impact areas.

Main Methods:

  • Analyzed EU CORDIS database (Horizon 2020).
  • Conducted expert analysis in environmental endocrinology.
  • Integrated literature review, epidemiological evidence, and emerging research.

Main Results:

  • Priorities include endocrine-disrupting chemicals (EDCs), pharmaceutical contamination, climate change, and pollution effects.
  • Focus on developmental programming, transgenerational effects, and public health policy.
  • Environmental factors fundamentally impact multiple endocrine systems.

Conclusions:

  • Provides an evidence-based roadmap for strategic research investment.
  • Highlights the need for coordinated research on environmental impacts on endocrine systems.
  • Supports aligning research funding with endocrine health priorities.