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EndoCompass project: endocrinology across the lifespan.
Evelien F Gevers1,2, Martine Cools3,4, Anita C Hokken-Koelega5
1Centre for Endocrinology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, United Kingdom.
European Journal of Endocrinology
|October 17, 2025
Summary
Endocrine science research needs strategic prioritization across all life stages to address hormone health challenges. The EndoCompass project identified key priorities for European research funding, emphasizing lifespan approaches for better health outcomes.
Area of Science:
- Endocrinology and hormone health research.
Background:
- Endocrine science is under-represented in European Union research programs.
- A gap exists between the societal impact of endocrine disorders and research funding prioritization.
- The EndoCompass project aimed to identify strategic research priorities in endocrine science.
Purpose of the Study:
- To identify and promote strategic research priorities in endocrine science.
- To address critical hormone-related health challenges across the lifespan.
- To provide an evidence-based roadmap for hormone regulation research.
Main Methods:
- Analysis of the EU CORDIS database for the Horizon 2020 framework (2014-2020).
- Expert analysis of endocrine regulation and health from gametogenesis to aging.
- Integration of evidence across developmental stages.
Main Results:
- Key research priorities include epigenetic programming, developmental origins of adult disease, brain-gut communication, and endocrine aspects of healthy aging.
- Emphasis on critical developmental windows and transgenerational effects.
- Need for integrated research spanning pediatric and adult endocrinology.
Conclusions:
- Coordinated, lifespan research is crucial for addressing Europe's demographic and health challenges.
- Strategic investment in endocrine health across all life stages is supported by the findings.
- The EndoCompass project provides a roadmap for future endocrine research and funding.
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