Healthcare resource utilization and cost in pediatric celiac disease: A case-control study using German insurance...

Area of Science:

• Pediatric Gastroenterology
• Health Economics
• Public Health

Background:

• Celiac disease (CeD) is a chronic immune disorder with limited data on its pediatric burden in Germany.
• Understanding healthcare resource utilization (HCRU) and costs is crucial for effective management.

Purpose of the Study:

• To assess the HCRU and healthcare costs associated with newly diagnosed pediatric CeD in Germany.
• To compare resource use and expenses in children with CeD versus matched controls.

Main Methods:

• Retrospective case-control study using German Statutory Health Insurance claims data (2014-2021).
• Compared HCRU (hospitalizations, outpatient contacts, prescriptions) and costs for CeD patients (<6 and 6-11 years) with matched non-CeD controls (1:5 ratio).
• Analysis covered the diagnosis period and two years post-diagnosis.

Main Results:

• Identified 410 CeD cases with incidence rates of 32.5-34.1 per 100,000 individuals.
• CeD patients showed significantly higher HCRU, including more hospitalizations, outpatient contacts, and prescriptions.
• Total healthcare costs were substantially higher for CeD patients (median difference €1677 and €1343 in younger and older groups, respectively).

Conclusions:

• Pediatric celiac disease imposes a significant burden on both patients and the healthcare system in Germany.
• Findings emphasize the need for targeted interventions and improved management strategies for CeD in children.