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Controlled Assembly of Gold Nanodiscs via DNA Hybridization: Tuning Plasmonic Coupling via Interparticle Gap Distance
Melda Taspika1, Takehiro Yachi2,3, Xu Shi2,4
1Graduate School of Life Science, Hokkaido University, Sapporo 060-0810, Japan.
Langmuir : the ACS Journal of Surfaces and Colloids
|October 17, 2025
Summary
This study demonstrates a DNA-guided method to assemble gold nanodiscs (AuNDs) into tunable 1D structures. Precise control over interparticle gap distances and multimerization allows fine-tuning of plasmonic coupling for advanced materials.
Area of Science:
- Nanotechnology
- Plasmonics
- Biomaterials Engineering
Background:
- Metal nanoparticle assemblies exhibit interparticle plasmonic coupling.
- Controlling this coupling is essential for plasmonic material applications.
- DNA-mediated assembly offers precise spatial control.
Purpose of the Study:
- To develop a method for precisely tuning plasmonic coupling in gold nanodisc assemblies.
- To investigate the influence of interparticle gap distance and multimerization on plasmonic coupling strength.
- To explore DNA ligand length and salt concentration for controlling assembly and disassembly.
Main Methods:
- Functionalizing gold nanodiscs (AuNDs) with complementary DNA ligands (+)-DNA and (-)-DNA.
- Assembling AuNDs into 1D cylindrical structures via DNA hybridization.
- Varying interparticle gap distances using DNA strands of different lengths (8, 11, 20 base pairs).
- Modulating assembly/disassembly temperatures via salt concentration and DNA ligand length.
- Tuning multimerization degree by adjusting DNA:AuND molar ratios and salt concentration.
Main Results:
- Achieved strong plasmonic coupling in AuND assemblies due to a 5.7 nm interparticle gap.
- Demonstrated fine-tuning of plasmonic coupling strength by adjusting interparticle gap distance.
- Showcased control over assembly/disassembly temperatures and degree of multimerization.
- Observed significant peak shifts in extinction spectra correlating with plasmonic coupling.
Conclusions:
- Presents a simple and effective method for tuning plasmonic coupling in AuND assemblies.
- Highlights the potential for expanding applications of plasmonic materials through controlled assembly.
- DNA-mediated self-assembly provides a versatile platform for nanostructure design.
