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A performance analysis of convolutional autoencoder modified WaveGAN architectures for realistic 12 lead
Jiaqi Liu1, Kwok Tai Chui2, Lap-Kei Lee1
1School of Science and Technology, Hong Kong Metropolitan University, Ho Man Tin, Kowloon, Hong Kong SAR, China.
Scientific Reports
|October 17, 2025
Summary
A new Convolutional Autoencoder-WaveGAN (CAE-WaveGAN) generates realistic electrocardiogram (ECG) images to overcome data scarcity for deep learning in cardiovascular diagnosis.
Area of Science:
- Artificial Intelligence
- Biomedical Engineering
- Medical Imaging
Background:
- Deep learning for cardiovascular diagnosis requires large, diverse electrocardiogram (ECG) datasets.
- Patient data confidentiality and scarcity impede the creation of comprehensive ECG datasets.
- Synthetic data generation can enhance deep learning model performance.
Purpose of the Study:
- To introduce a novel Convolutional Autoencoder-WaveGAN (CAE-WaveGAN) for generating synthetic 12-lead ECG images.
- To address the challenge of ECG data scarcity in clinical diagnostics.
- To improve the development of deep learning models for cardiovascular disease detection.
Main Methods:
- A Convolutional Autoencoder (CAE) was used for efficient feature extraction from ECG signals.
- A WaveGAN generator synthesized high-fidelity ECG images using extracted features.
- Ablation studies were performed on the CODE-15% dataset to analyze CAE-WaveGAN configurations.
Main Results:
- CAE-WaveGAN demonstrated superior performance across all evaluation metrics.
- Significant improvements were observed: 19.8% in Peak Signal-to-Noise Ratio (PSNR) and 59.3% in Structural Similarity Index Measure (SSIM).
- The optimal CAE-WaveGAN architecture showed improved stability and loss metrics compared to traditional WaveGAN.
Conclusions:
- CAE-WaveGAN offers a practical solution for expanding ECG datasets while preserving patient privacy.
- The method effectively generates realistic ECG data for clinical machine learning applications.
- This approach facilitates the development of more robust deep learning models for cardiovascular diagnosis.
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