Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

8.9K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
8.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A High Level of Calculated Small Dense Low-Density Lipoprotein Cholesterol Is an Independent Risk Factor for the Progression of Renal Impairment.

Circulation journal : official journal of the Japanese Circulation Society·2026
Same author

A rare case of persistent sciatic artery associated with arteriosclerotic occlusive disease.

Journal of surgical case reports·2026
Same author

A Salvage Hybrid Reconstruction Using Covered Stents for Internal Iliac Artery Preservation during Endovascular Aneurysm Repair in a Patient with an Extremely Short Common Iliac Artery: A Case Report.

Annals of vascular diseases·2026
Same author

Impact of Hormonal and Radiation Therapy on Bladder Outlet Obstruction in High-Risk Localized Prostate Cancer: A Prospective Pressure-Flow Study.

International journal of urology : official journal of the Japanese Urological Association·2026
Same author

Impact of surgical assistance by Japanese nurse practitioners in robotic-assisted coronary artery bypass graft surgery.

Journal of robotic surgery·2026
Same author

Preoperative frontal lobe and global cognitive function as predictors of postoperative delirium after cardiovascular surgery: a predictive and exploratory mediation analysis.

Heart and vessels·2026

Related Experiment Video

Updated: Jan 6, 2026

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
11:16

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Published on: February 25, 2022

3.7K

Left atrial appendage blood flow analysis using four-dimensional flow magnetic resonance imaging.

Akihito Ohkawa1, Tomohiro Nakajima2, Shingo Tsushima2

  • 1Department of Cardiovascular Surgery, Sapporo Medical University, Minami 1 Jo Nishi 17 Chome 291, Chuou-ku, Sapporo, Hokkaido, Japan. akihito.ookawa7719@gmail.com.

General Thoracic and Cardiovascular Surgery
|October 18, 2025
PubMed
Summary

Blood flow stagnation in the left atrial appendage (LAA) top segment occurs in high-risk patients even with sinus rhythm. This finding may improve stroke prevention strategies using LAA closure.

Keywords:
Blood flowFour-dimensional magnetic resonanceLeft atrial appendage

More Related Videos

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

2.0K
High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation
09:17

High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation

Published on: July 29, 2011

15.2K

Related Experiment Videos

Last Updated: Jan 6, 2026

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
11:16

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Published on: February 25, 2022

3.7K
Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

2.0K
High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation
09:17

High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation

Published on: July 29, 2011

15.2K

Area of Science:

  • Cardiology
  • Medical Imaging

Background:

  • Blood flow stagnation in the left atrial appendage (LAA) is a primary cause of thrombus formation in atrial fibrillation.
  • Stagnant LAA flow is also suspected in patients with sinus rhythm and elevated stroke risk.

Purpose of the Study:

  • To evaluate LAA blood flow using 4D flow MRI in patients stratified by CHA2DS2-VASc scores.
  • To identify correlations between stroke risk factors and LAA hemodynamics.

Main Methods:

  • Ninety-eight participants (70 patients, 28 controls) with sinus rhythm underwent non-contrast 4D flow MRI.
  • Participants were categorized into low (CHA2DS2-VASc 0-2) and high (CHA2DS2-VASc 3-9) risk groups.
  • LAA blood flow volume in basal, middle, and top segments was analyzed and compared.

Main Results:

  • Significantly reduced blood flow volume was observed in the LAA top segment of the high-risk group compared to the low-risk group (p=0.006).
  • No significant differences in blood flow volume were found in the basal and middle LAA segments between groups.
  • Larger LAA volumes correlated with reduced top-segment flow, but not significantly with intra-LAA flow.

Conclusions:

  • High CHA2DS2-VASc scores are associated with LAA top segment blood flow stagnation, even in sinus rhythm.
  • Developing blood flow-based criteria could enhance LAA closure applications for stroke prevention.