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Updated: Jan 14, 2026

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Side-Chain Macrocyclization in Ahp-Bicyclodepsipeptides Biosynthesis Involves Cytochrome P450-Catalyzed Sequential

Qiang Dong1, Niandi Zhang2, Xiaorong Chen1

  • 1Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, Guangdong, 528400, China.

Angewandte Chemie (International Ed. in English)
|October 18, 2025
PubMed

Keywords:
BiosynthesisC─N couplingGenome miningNonribosomal peptidesSide‐chain macrocyclization

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