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Experienced benefits and side effects affect adherence with long-term noninvasive ventilation.
Heidi A Rantala1, Sirpa Leivo-Korpela2, Carlijn Beerling3
1Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland; Department of Respiratory Medicine, Tampere University Hospital, Wellbeing Services County of Pirkanmaa, Tampere, Finland.
Adherence to long-term noninvasive ventilation (LT-NIV) in COPD, OHS, and ALS patients is linked to perceived benefits and fewer side effects. Early, optimized follow-up can improve patient adherence to LT-NIV.
Area of Science:
- Respiratory Medicine
- Pulmonology
- Critical Care
Background:
- Long-term noninvasive ventilation (LT-NIV) is a key therapy for hypoventilation across various diseases.
- Understanding adherence factors is crucial for optimizing LT-NIV effectiveness.
Purpose of the Study:
- To investigate factors influencing adherence to LT-NIV in patients with COPD, OHS, and ALS.
- To assess the impact of adherence on survival in these patient groups.
Main Methods:
- Retrospective study of 702 patients initiating LT-NIV across Finland and the Netherlands.
- Follow-up duration of two years, analyzing adherence rates and survival data.
Main Results:
- Adherence rates at six months varied: 78% for COPD, 67% for OHS, and 87% for ALS.
- Perceived benefits, fewer side effects, and treatment hospital were associated with better adherence.
- Survival rates did not significantly differ between adherent and non-adherent patients.
Conclusions:
- Patient-reported benefits and tolerance (fewer side effects) are key drivers of LT-NIV adherence.
- Adherence to LT-NIV did not impact short-term survival in the studied populations.
- Proactive and optimized patient follow-up from initiation is recommended to enhance adherence.
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