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Real-world diagnostic performance of knee MRI protocols accelerated using simultaneous multi-slice acquisition and
Patricia M Johnson1,2, Siddhant Dogra3, Malte Westerhoff4
1Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, USA. patricia.johnson3@nyulangone.org.
Accelerated knee MRI using simultaneous multi-slice (SMS) and deep learning reconstruction (DLR) shows comparable diagnostic performance to conventional methods for detecting internal derangements. These faster protocols support wider clinical use for efficient knee imaging.
Area of Science:
- Radiology
- Medical Imaging
- Orthopedics
Background:
- Knee internal derangements require accurate MRI diagnosis.
- Conventional MRI protocols can be time-consuming, limiting patient throughput.
- Accelerated MRI techniques offer potential for faster scan times without compromising diagnostic quality.
Purpose of the Study:
- To evaluate the non-inferiority of accelerated knee MRI protocols (SMS and SMS with DLR) compared to conventional parallel imaging for detecting internal derangements.
- To assess the diagnostic performance (sensitivity and specificity) of these accelerated protocols against arthroscopy as the reference standard.
Main Methods:
- Retrospective cohort study of 1055 patients undergoing knee MRI followed by arthroscopy.
- Comparison of three MRI protocols: conventional, accelerated SMS, and accelerated SMS with DLR.
- Analysis of sensitivity and specificity for anterior cruciate ligament (ACL), medial meniscus (MM), and lateral meniscus (LM) tears.
Main Results:
- Accelerated protocols showed higher sensitivity for ACL tears (0.96-0.98) versus conventional (0.85), confirming non-inferiority.
- Sensitivity for MM tears met non-inferiority criteria (0.94-0.95).
- While not all metrics met the strict non-inferiority margin, no statistically significant reduction in sensitivity or specificity was observed across protocols.
Conclusions:
- Accelerated knee MRI protocols using SMS and DLR demonstrate comparable diagnostic performance to conventional methods.
- These findings support the clinical adoption of accelerated MRI for efficient, high-throughput knee imaging.
- Further optimization may be needed to consistently meet strict non-inferiority margins for all specific knee injuries.
