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Two-stage Adaptive Enrichment Designs with Survival Outcomes and Adjustment for Misclassification in Predictive

Yanping Chen1, Yong Lin2, Shou-En Lu2

  • 1Biostatistics and Data Management, Regeneron Pharmaceuticals, Baskin Ridge, New Jersey, USA.

Statistics in Biopharmaceutical Research
|October 20, 2025
PubMed

Keywords:
Adaptive enrichment designsComposite HypothesisPredictive BiomarkerSensitivity and SpecificitySurvival Outcome

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