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Pseudoprogression of Non-Small Cell Lung Cancer Following Neoadjuvant Therapy: A Case Report

Kareem Ramadan1, Mona Benaissa2, Michael Shackcloth1

  • 1Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, Liverpool, GBR.

Cureus
|October 20, 2025
PubMed
Summary

Neoadjuvant chemoimmunotherapy for early-stage non-small cell lung cancer (NSCLC) can cause radiological progression, mimicking tumor growth. Recognizing pseudoprogression is crucial, as it may allow patients to still receive potentially curative surgery.

Keywords:
lung adenocarcinomaneoadjuvant therapynosnsclcradiological pseudo progression

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