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A Rare Case of Adult Escherichia coli Meningitis Following Endoscopic Skull-Base Surgery
Devi B Yalamanchili1,2, Holly O'Brien1,2, Bushra Shariff1,2
1Internal and Hospital Medicine, Moffitt Cancer Center, Tampa, USA.
Abstract:
This report describes the case of a 65-year-old male who developed Escherichia coli (E. coli) meningitis after endoscopic resection of a sinonasal neuroblastoma, complicated by a cerebrospinal fluid (CSF) leak, pneumocephalus, and subsequent concurrent infection with Actinomyces odontolyticus. The patient underwent prolonged, tailored antibiotic therapy and surgical CSF leak repair. The report highlights the importance of suspecting E. coli meningitis in post-neurosurgical patients, emphasizes the need for prompt management of CSF leaks, and underscores the need for vigilance regardless of immunocompetency. The patient fortunately survived with a favorable outcome thanks to early diagnosis, immediate intervention, and careful antibiotic management.
Insights
A rare case of Escherichia coli (E. coli) meningitis occurred after neurosurgery, complicated by a cerebrospinal fluid leak. Prompt diagnosis and treatment led to a favorable outcome for the patient.
Area of Science:
- Neuroscience
- Infectious Diseases
- Neurosurgery
Background:
- Post-neurosurgical infections, particularly meningitis, pose significant risks.
- Cerebrospinal fluid (CSF) leaks are a known complication following sinonasal surgery.
- Concurrent infections can complicate the clinical picture and treatment strategies.

