Central Giant Cell Granuloma of the Posterior Maxilla

Central giant cell granuloma (CGCG) is an uncommon, benign, proliferative intraosseous lesion of the jaws with an uncertain etiology. It is more frequently reported in the mandible, whereas maxillary involvement is relatively rare. We present the case of a 30-year-old female patient with a swelling in the right posterior maxilla that had gradually increased in size over a year. Clinical examination revealed a firm, tender, and expansile lesion, while radiographic evaluation demonstrated a well-defined radiolucent lesion associated with the maxillary posterior teeth. Histopathological analysis confirmed the diagnosis of a CGCG. The lesion was surgically treated with enucleation, curettage, and peripheral ostectomy under general anesthesia. This case underscores the significance of correlating clinical, radiological, and histopathological features for the accurate diagnosis of maxillary lesions and highlights surgical management as an effective treatment modality for CGCG.