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Updated: Jan 14, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Cardiovascular Information and Health Engineering Medicine
Xue Bao1,2, Ziyu Zhang1,2, Yuhe Shen1
1Department of Cardiology, Cardiovascular Disease Center, Jiangsu Key Laboratory for Cardiovascular Information and Health Engineering Medicine, Nanjing Drum Tower Hospital, Medical School, Nanjing University, Nanjing 210093, P. R. China.
None:
Cardiovascular diseases (CVDs) persistently impose a substantial global health burden, highlighting the necessity for innovative approaches to their prevention, diagnosis, and treatment. This paper accentuates the close correlation between vascular health and CVDs. To address unmet clinical demands for the early and efficient management of CVDs, we emphasize the potential of engineering medicine and propose the concept of cardiovascular information and health engineering medicine (CVIHEM), delineating its objectives and framework for collecting, analyzing, and translating multidimensional vascular data into practical strategies. By systematically and efficiently acquiring and translating vascular information through multidisciplinary collaboration, CVIHEM enhances our understanding of the vascular network and provides innovative strategies for promoting vascular health. This approach encompasses a range of applications, such as artificial intelligence-driven decision-making, targeted therapy, and vascular health management, ultimately improving vascular health and clinical outcomes.
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