Application of platelet-rich plasma in treating refractory wounds following hemorrhoid surgery: a case report

This case report presents the successful application of autologous Platelet-rich Plasma (PRP) in treating a 53-year-old male patient with a nonhealing perianal wound that persisted for 71 days following surgery for mixed hemorrhoid and anal fistula, despite conventional therapies, including topical traditional Chinese medicine, antibiotics, and wound care. A series of three PRP treatments, administered on October 25, October 27, and November 1, 2023, accelerated healing, resulting in complete closure of the 1.6 cm wound within 14 days. This was accompanied by reduced pain and no recurrence at follow-up, demonstrating PRP's effectiveness in promoting tissue regeneration, controlling infection, and relieving pain in a refractory post-surgical wound.