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Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics
Published on: July 16, 2018
Revolutionizing healthcare with nanosensor technology
Nakshatra Bahadur Singh1, Asima Monjur2,3, Bhuvnesh Kumar1
1Research Development Cell, Sharda University Greater Noida India n.b.singh@sharda.ac.in.
Abstract:
Modern healthcare is constantly evolving due to the inclusion of many smart technologies. Nanotechnology, since its inception, has tremendous influence on this transformation. With an emphasis on healthcare applications, the current review explores recent advancements in nanomaterial-based biosensors. The tunability of nanomaterials provides control over the chemical, mechanical, thermal, and electrical properties, thus presents nanotechnology as a more promising solution to develop smart sensing, monitoring, and diagnostics. The synergistic effects and regulated interaction with a variety of bioanalytes spurred the advancements of nano empowered devices with high selectivity and sensitivity. With a focus on common nanomaterials e.g., metal and metal oxides, graphene and polymer-based nanomaterials, the review comprehensively discusses fundamentals of nano enabled biosensors and their classification based on methods of detection. Insight has been provided exploring the potential of various types of nanomaterials harnessed in the development of pioneering sensor designs in recent times. Along with addressing the current limitations, future prospects are discussed to redefine the landscape of nanobiosensors.

