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The correlation between the styloid process length, angle, head shape, and eagle syndrome based on high-resolution CT
Jiaqi Duan1, Fang Wu2, Linfeng Liu3
1The Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Frontiers in Medicine
|October 20, 2025
Summary
A new R value index accurately diagnoses Eagle Syndrome by measuring styloid process length and angles. This composite index shows high diagnostic efficacy, aiding clinical suspicion and diagnosis.
Area of Science:
- Radiology and Imaging
- Anatomy
- Medical Diagnostics
Background:
- Eagle Syndrome (ES) is characterized by styloid process (SP) abnormalities.
- Accurate diagnosis relies on identifying SP length and spatial orientation.
- Existing diagnostic methods may lack comprehensive quantitative assessment.
Purpose of the Study:
- To develop and validate a comprehensive evaluation index (R value) for diagnosing Eagle Syndrome.
- To assess the diagnostic value of the R value based on SP length and spatial angles.
- To explore the imaging and clinical features of Eagle Syndrome.
Main Methods:
- Retrospective analysis of high-resolution CT (HRCT) data from 57 ES patients and 49 controls.
- Measurement of bilateral SP length, inward angulation, and forward tilt angle.
- Calculation of the R value and assessment of its diagnostic efficacy using ROC curve analysis and binary logistic regression.
Main Results:
- Patients with Eagle Syndrome showed significantly increased SP length, inward angulation, and forward tilt angle compared to controls.
- The R value demonstrated high diagnostic efficacy with an AUC of 0.86 for the left and 0.82 for the right side.
- Optimal cutoff values for the R value were identified for both sides, with high sensitivity and specificity.
Conclusions:
- Eagle Syndrome is strongly associated with specific styloid process length and angle measurements.
- The R value, integrating key anatomical parameters, is a valuable tool for diagnosing Eagle Syndrome.
- The R value serves as a quantitative reference criterion for diagnosing Eagle Syndrome, particularly when left R > 2.85 and/or right R > 2.72.

