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Updated: Jan 14, 2026

Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction
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Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction

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Hydrochalcogenation Reactions with Noncanonical Amino Acids as a Route to Increase Bioconjugate Valency

Emily L Boyt1, Tyler L Skeen1, Cedrick R Dimaranan1

  • 1Department of Chemistry, William & Mary, Williamsburg, Virginia 23185, United States.

ACS Omega
|October 20, 2025
PubMed
Abstract

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