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Related Concept Videos

Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

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Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
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Endoscopic Procedures II: Colonoscopy01:25

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The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
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Related Experiment Video

Updated: Jan 14, 2026

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
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AGA Clinical Practice Update on Endoscopic Resection for Early Colorectal Cancer: Commentary.

Saowanee Ngamruengphong1, Mohamed O Othman2, Andrew Y Wang3

  • 1Division of Gastroenterology and Hepatology, Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland.

Gastroenterology
|October 20, 2025
PubMed
Summary
This summary is machine-generated.

T1 colorectal cancer (CRC) management has evolved beyond surgery. Endoscopic resection is now a viable option for early-stage CRC, with careful consideration of recurrence and metastasis risk guiding post-procedure care.

Keywords:
AdenocarcinomaColorectal CancerEndoscopic Mucosal ResectionEndoscopic Submucosal Dissection

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Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
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Area of Science:

  • Gastroenterology
  • Oncology
  • Surgical Pathology

Background:

  • T1 colorectal cancer (CRC), characterized by submucosal invasion, was historically treated surgically.
  • Recent advancements in endoscopic resection and understanding of CRC biology have broadened treatment options.

Purpose of the Study:

  • To review the definition and diagnostic criteria for T1 CRC.
  • To evaluate the efficacy and indications for endoscopic resection in T1 CRC.
  • To discuss risk stratification for metastasis and recurrence, and guide post-resection management strategies.

Main Methods:

  • Expert commentary and clinical practice update.
  • Review of current literature on T1 CRC diagnosis, treatment, and management.
  • Synthesis of evidence to provide guidance for healthcare professionals.

Main Results:

  • Endoscopic resection is increasingly utilized for select T1 CRC cases.
  • Risk factors for lymph node metastasis and recurrence are crucial for treatment decisions.
  • Post-resection management involves surveillance or adjuvant surgery based on risk assessment.

Conclusions:

  • Management of T1 CRC requires a multidisciplinary approach, integrating endoscopic and surgical options.
  • Accurate risk stratification is essential for optimizing patient outcomes after resection.
  • This AGA expert commentary provides updated guidance for clinicians managing T1 CRC.