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Generation of induced pluripotent stem cell line UJSi005-A from developmentally delayed schizophrenic patients
Xuan Xu1, Bing Xue1, Dingqi Zhang1
1Neurobiology & Mitochondrial Key Laboratory, Effective & Toxicity Monitoring Innovative Practice Center for Food Pharmaceutical Specialty, School of Pharmacy, Jiangsu University, Zhenjiang 212013, PR China.
None:
Schizophrenia, a chronic mental health condition, is characterized by abnormalities in perception, emotions and behavior. We successfully generated induced pluripotent stem cells (iPSCs) from the peripheral blood mononuclear cells (PBMCs) of a patient with schizophrenia and neurodevelopmental delay who responded well to olanzapine therapy. The iPSCs exhibited a normal karyotype, expressed markers of undifferentiated human pluripotent stem cells (hPSCs), and differentiated into the three germ layers in vivo.
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