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Updated: Jun 18, 2026

Capillary Electrophoresis to Monitor Peptide Grafting onto Chitosan Films in Real Time
Published on: October 26, 2016
Structure-Property-Application framework for multifunctional chitosan across biomedical, environmental, and
Qonita Deifaky Tsauria1, Paulus Lobo Gareso1, Dahlang Tahir1
1Department of Physics, Hasanuddin University, Makassar, 90245, Indonesia.
Abstract:
Chitosan, a naturally derived biopolymer, holds significant promise for advancing material innovation across biomedical, environmental, food, and technological sectors. Its structural tunability-particularly through variations in degree of deacetylation and molecular weight-governs key physicochemical properties such as solubility, charge density, and mechanical performance. These features, along with chemical modifications including quaternization, thiolation, and carboxymethylation, enable chitosan to support a broad array of applications such as hydrogels, pollutant-adsorbing composites, antimicrobial coatings, and bioelectronic materials. This review analyzes 64 studies published between 2020 and 2024, selected from over 5000 screened articles for their exclusive focus on chitosan without hybrid additives. Using a Structure-Property-Application (SPA) framework, the review explores how molecular design influences material performance in diverse contexts. While challenges such as limited solubility in neutral and basic media persist, recent advancements in functionalization continue to enhance chitosan's applicability. By synthesizing insights from materials design and domain-specific innovations, this work highlights chitosan's potential as a foundational material for next-generation solutions.
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