Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Contact-dependent Signaling01:19

Contact-dependent Signaling

46.8K
Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
Gap Junctions
In animal cells, gap junctions are formed...
46.8K
Cyclic Processes And Isolated Systems01:19

Cyclic Processes And Isolated Systems

3.4K
A thermodynamic system with zero heat exchange and work is an isolated system. For these systems, the internal energy remains constant.
In the case of a non-isolated system, the change in the internal energy is zero only if the process is cyclic. A thermodynamic process is considered cyclic if the system undergoes a series of changes and returns to its initial state. 
Consider a cyclic process that returns to its initial state, undergoing a four-step process. The heat transfer along each...
3.4K
Basic Continuous Time Signals01:22

Basic Continuous Time Signals

664
Basic continuous-time signals include the unit step function, unit impulse function, and unit ramp function, collectively referred to as singularity functions. Singularity functions are characterized by discontinuities or discontinuous derivatives.
The unit step function, denoted u(t), is zero for negative time values and one for positive time values, exhibiting a discontinuity at t=0. This function often represents abrupt changes, such as the step voltage introduced when turning a car's...
664
Convolution: Math, Graphics, and Discrete Signals01:24

Convolution: Math, Graphics, and Discrete Signals

823
In any LTI (Linear Time-Invariant) system, the convolution of two signals is denoted using a convolution operator, assuming all initial conditions are zero. The convolution integral can be divided into two parts: the zero-input or natural response and the zero-state or forced response, with t0 indicating the initial time.
To simplify the convolution integral, it is assumed that both the input signal and impulse response are zero for negative time values. The graphical convolution process...
823
Modeling with Differential Equations01:25

Modeling with Differential Equations

4
Population dynamics can be described mathematically by considering the population size P(t) as a function of time. The rate of change of the population is then represented by the derivative of P(t). A simple assumption is that the rate of growth is proportional to the size of the population itself. This leads to an exponential growth model, where the population increases rapidly without bound. While this is a useful first approximation, it does not reflect realistic long-term...
4
Classification of Systems-II01:31

Classification of Systems-II

457
Continuous-time systems have continuous input and output signals, with time measured continuously. These systems are generally defined by differential or algebraic equations. For instance, in an RC circuit, the relationship between input and output voltage is expressed through a differential equation derived from Ohm's law and the capacitor relation,
457

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Use of Metabotyping to Identify Individuals With Different Triglyceride Response Curves After Intake of High-Fat Meals.

Molecular nutrition & food research·2026
Same author

Federated Learning over MU-MIMO Vehicular Networks.

Entropy (Basel, Switzerland)·2025
Same author

Usefulness of Point-Of-Care Ultrasound in Diagnosing and Managing Pediatric Multidistrict Chylous Effusion.

Reports (MDPI)·2025
Same author

Lung Ultrasound Score and Bronchiolitis: What can be Predicted in a Single Center Experience.

Journal of intensive care medicine·2025
Same author

Association between early radiographic chest findings and clinical outcomes in pediatric drowning: a retrospective study in a tertiary Italian hospital.

European journal of pediatrics·2025
Same author

Finding patient zero in susceptible-infectious-susceptible epidemic processes.

Physical review. E·2024

Related Experiment Video

Updated: Jan 14, 2026

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface
11:54

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Published on: May 8, 2021

5.1K

Continuous-time process for human contact dynamics.

Robin Persoons1, Matteo D'Alessandro1, Piet Van Mieghem1

  • 1Delft University of Technology, Faculty of Electrical Engineering, Mathematics and Computer Science, P.O. Box 5031, 2600 GA Delft, The Netherlands.

Physical Review. E
|October 21, 2025
PubMed
Summary
This summary is machine-generated.

We introduce a continuous-time Markov model for human contact dynamics, the continuous random walkers induced temporal graph model (CRWIG). This model captures complex human mobility patterns, including arbitrary flight and pause times, with a non-Markovian extension.

More Related Videos

Trajectory Data Analyses for Pedestrian Space-time Activity Study
16:14

Trajectory Data Analyses for Pedestrian Space-time Activity Study

Published on: February 25, 2013

14.1K
The HoneyComb Paradigm for Research on Collective Human Behavior
06:48

The HoneyComb Paradigm for Research on Collective Human Behavior

Published on: January 19, 2019

9.8K

Related Experiment Videos

Last Updated: Jan 14, 2026

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface
11:54

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Published on: May 8, 2021

5.1K
Trajectory Data Analyses for Pedestrian Space-time Activity Study
16:14

Trajectory Data Analyses for Pedestrian Space-time Activity Study

Published on: February 25, 2013

14.1K
The HoneyComb Paradigm for Research on Collective Human Behavior
06:48

The HoneyComb Paradigm for Research on Collective Human Behavior

Published on: January 19, 2019

9.8K

Area of Science:

  • Complex Systems
  • Network Science
  • Stochastic Processes

Background:

  • Human contact dynamics are crucial for understanding disease spread and social interactions.
  • Existing models often simplify mobility patterns, limiting their real-world applicability.

Purpose of the Study:

  • To develop a novel continuous-time Markov model for human contact dynamics.
  • To analyze the emergent properties of walker interactions and contact graph formation.
  • To extend the model for non-Markovian behaviors and compare with empirical human mobility data.

Main Methods:

  • Development of the continuous random walkers induced temporal graph (CRWIG) model.
  • Mathematical formulation of the Markov governing equation for walker ensemble.
  • Analysis of time discretization effects and proof of exponential decay and intermeeting time tails.
  • Extension to a non-Markovian model with non-exponential sojourn times.

Main Results:

  • CRWIG exhibits exponential decay of initial conditions and exponentially tailed intermeeting times.
  • The non-Markovian extension accurately reproduces empirical human mobility: arbitrary flight/pause distributions.
  • The extended model yields power-law intermeeting time distributions with exponential tails.

Conclusions:

  • The CRWIG model provides a robust framework for studying human contact dynamics.
  • The non-Markovian extension significantly enhances the model's ability to capture real-world human mobility.
  • This work offers valuable insights for fields like epidemiology, urban planning, and social network analysis.