Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

916
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
916
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

473
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
473
Ethics in Research01:56

Ethics in Research

25.4K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
25.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A review of the randomized clinical trial results from the Staphylococcus aureus network adaptive platform (SNAP) meticillin-susceptible (MSSA) and penicillin-susceptible (PSSA) domains and CloCeBa.

The Journal of antimicrobial chemotherapy·2026
Same author

Cefazolin for Methicillin-Susceptible <i>Staphylococcus aureus</i> Bacteremia.

The New England journal of medicine·2026
Same author

Determinants affecting the quality of sexual life among older adults in Africa: a scoping review.

Sexual health·2026
Same author

Online sexual health survey implementation: Practical lessons from a comparative, mixed-methods analysis of 30 countries.

PloS one·2026
Same author

Adolescent and young adult participation in HIV self-testing: secondary analysis of cross-sectional data from Nigeria.

Sexual health·2026
Same author

Diversity and inclusion at scientific conferences.

Sexual health·2026
Same journal

Ebola laboratory preparedness at frontline hospitals: can we or can't we?

Journal of clinical microbiology·2026
Same journal

Reporting macrolide-resistant <i>Mycoplasma pneumoniae</i>: a diagnostic obligation?

Journal of clinical microbiology·2026
Same journal

Diagnostic value of HHV-6A/B genotyping in immunocompromised adults.

Journal of clinical microbiology·2026
Same journal

Multicenter performance evaluation of the Simplexa <i>C. auris</i> Direct assay for the detection of <i>Candida auris</i> colonization in bilateral axilla/groin swabs.

Journal of clinical microbiology·2026
Same journal

Comparison of blood culture contamination rates with standard practice versus two blood diversion devices at a single institution.

Journal of clinical microbiology·2026
Same journal

Risk assessment and mitigation of hepatitis C virus RNA carryover contamination in a reflex testing algorithm.

Journal of clinical microbiology·2026
See all related articles

Related Experiment Video

Updated: Jan 14, 2026

Author Spotlight: Advancing Syphilis Research &#8212; Innovations in Treponema pallidum Cultivation and Genetic Engineering
09:45

Author Spotlight: Advancing Syphilis Research — Innovations in Treponema pallidum Cultivation and Genetic Engineering

Published on: January 24, 2025

6.8K

Syphilis self-testing and implications for syphilis control and prevention.

Ayel Luis R Batac1,2, Michael Marks3,4,5, Joseph D Tucker2,3,6,7

  • 1Faculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Journal of Clinical Microbiology
|October 21, 2025
PubMed
Summary
This summary is machine-generated.

Syphilis self-tests (SSTs) are accurate and acceptable, offering a new way to improve syphilis diagnosis. However, challenges like equitable access and linkage to care must be addressed for successful implementation.

Keywords:
Treponema pallidumdiagnosticsover-the-counter syphilis testrapid syphilis testself-testsyphilis

More Related Videos

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling
08:26

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling

Published on: June 23, 2022

2.0K
Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
23:56

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

17.1K

Related Experiment Videos

Last Updated: Jan 14, 2026

Author Spotlight: Advancing Syphilis Research &#8212; Innovations in Treponema pallidum Cultivation and Genetic Engineering
09:45

Author Spotlight: Advancing Syphilis Research — Innovations in Treponema pallidum Cultivation and Genetic Engineering

Published on: January 24, 2025

6.8K
Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling
08:26

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling

Published on: June 23, 2022

2.0K
Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
23:56

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

17.1K

Area of Science:

  • Public Health
  • Infectious Diseases
  • Diagnostic Technologies

Background:

  • Syphilis incidence is rising globally despite available treatments.
  • Over-the-counter syphilis self-tests (SSTs) have been approved, marking a significant step in diagnostics.
  • Existing diagnostic methods face challenges in accessibility and reach.

Purpose of the Study:

  • To evaluate the accuracy, usability, and acceptability of syphilis self-tests (SSTs).
  • To identify implementation challenges for SSTs in real-world settings.
  • To inform strategies for effective integration of SSTs into public health programs.

Main Methods:

  • Review of evidence on syphilis self-test (SST) accuracy.
  • Assessment of usability and acceptability studies for SSTs.
  • Analysis of implementation science literature for self-testing programs (HIV, COVID-19, syphilis).

Main Results:

  • Syphilis self-tests (SSTs) demonstrate high accuracy, usability, and acceptability.
  • Evidence supports SSTs as a valuable tool for expanding diagnostic access.
  • Key implementation challenges include ensuring equitable access, supporting vulnerable populations, and linkage to care.

Conclusions:

  • Syphilis self-tests (SSTs) offer a promising advancement for syphilis control and prevention.
  • Addressing implementation barriers is crucial for maximizing the public health impact of SSTs.
  • Continued research and strategic planning are needed for successful SST scale-up.