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Urodynamic Studies: Uroflowmetry01:19

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Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...
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Related Experiment Video

Updated: Jan 14, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
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Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

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Intraoperative Transit Time Flowmetry for Unruptured Middle Cerebral Artery Aneurysms.

Vladimir Priban1, Jiri Dostal2, Jan Mracek1

  • 1Department of Neurosurgery, Faculty of Medicine and University Hospital in Pilsen, Charles University, Czech Republic.

Neurologia I Neurochirurgia Polska
|October 21, 2025
PubMed
Summary

Intraoperative transit time flowmetry (ITTF) monitoring during middle cerebral artery (MCA) aneurysm clipping may enhance surgical safety by enabling critical clip adjustments. While not statistically significant, this technique aided in two cases where standard methods showed no issues.

Keywords:
aneurysmintraoperative monitoringischemiamiddle cerebral arterytransit time flowmetry

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Area of Science:

  • Neurosurgery
  • Vascular Surgery
  • Medical Devices

Background:

  • Clipping middle cerebral artery (MCA) aneurysms is challenging due to adjacent vessel proximity.
  • Cerebral blood flow monitoring is crucial to prevent ischemic complications.
  • Intraoperative transit time flowmetry (ITTF) offers real-time cerebral blood flow data.

Purpose of the Study:

  • To evaluate if ITTF monitoring improves outcomes in unruptured MCA aneurysm clipping.
  • To compare postoperative results between ITTF-monitored and non-monitored groups.

Main Methods:

  • Retrospective cohort study of 54 patients (2010-2019) undergoing MCA aneurysm clipping.
  • 34 patients with ITTF monitoring, 20 without.
  • ITTF used for real-time flow assessment; clip adjustments made if flow reduced >25%.

Main Results:

  • Postoperative morbidity: 3% (ITTF group) vs. 5% (control group).
  • Two ITTF-monitored cases required clip repositioning despite normal ICG and MEPs.
  • No statistically significant difference in neurological deficits between groups.

Conclusions:

  • ITTF monitoring may enhance surgical safety by detecting flow issues missed by standard methods.
  • Enabled clip repositioning in two critical cases.
  • Further research is needed to confirm clinical benefits and define ITTF's role.