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Interactions between Poisons, Patients, and Extracorporeal Blood Purification Therapies: A Comprehensive Analysis
Matteo Pernazza1, Gianluca Castellani2, Matteo Marrocu3
1Ospedale Maria SS Addolorata, ASL Salerno, Eboli, Italy.
Background:
Poisonings can harm through their direct effect or determining organ dysfunction. Extracorporeal blood purification therapies (EBPT) have been used for decades in case of poisonings. Although poisoning remains a major public health issue, focusing on organ dysfunction rather than the poison itself has significantly reduced mortality rates.
Summary:
This review explores the complex and dynamic interactions among poisons, patients, and EBPT and describes specific poisonings where EBPT may be indicated.
Key Messages:
EBPT are indicated in many cases of intoxication, either to enhance clearance or for organ support. A thorough understanding of the interactions between poisons, patients, and EBPT is mandatory for proper management of each specific intoxication.
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Renal excretion is the...
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