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The 2-deoxy-D-glucose-neutral red test and vagotomy: an experimental study
South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
|September 3, 1977
Summary
The 2-deoxy-D-glucose - neutral red test effectively assesses vagotomy completeness in baboons, showing no adverse effects. This method identified an incomplete parietal cell vagotomy in one human patient post-surgery.
Area of Science:
- Gastroenterology
- Surgical Assessment
- Diagnostic Testing
Background:
- Vagotomy is a surgical procedure involving the vagus nerve.
- Assessing the completeness of vagotomy is crucial for patient outcomes.
- Existing methods for assessing vagotomy completeness may have limitations.
Purpose of the Study:
- To evaluate the efficacy of the 2-deoxy-D-glucose - neutral red test.
- To determine if the test can accurately assess vagotomy completeness.
- To assess the safety and practicality of the test in clinical settings.
Main Methods:
- The 2-deoxy-D-glucose - neutral red test was employed.
- Testing was performed both intraoperatively and postoperatively in baboons.
- The test was also utilized in 5 human patients during the immediate postoperative phase.
Main Results:
- The 2-deoxy-D-glucose - neutral red test demonstrated success in assessing vagotomy completeness.
- No deleterious side-effects were observed from the test.
- The test successfully identified an incomplete parietal cell vagotomy in one patient.
Conclusions:
- The 2-deoxy-D-glucose - neutral red test is a viable tool for assessing vagotomy completeness.
- The test is safe, effective, and can be adequately sterilized.
- This diagnostic method aids in identifying surgical success or potential complications.