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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
Published on: August 15, 2019
MouseOmics: a multi-omics database for mouse biological study
Xin Tian1, Yifan Teng2, Miaomiao Huang3
1Key Laboratory of Animal Molecular Nutrition Ministry of Education, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
None:
Mouse represents a pivotal model and indispensable resource in medical and life sciences, widely used for developmental biology and multi-omics studies. Yet, a comprehensive, integrated mouse multi-omics database remains lacking. Here, we established a mouse multi-omics database, MouseOmics, by integrating 21 genomes distributed among five species within the genus Mus, transcriptomes in 584 tissue samples, proteomes in 285 tissue samples, metabolomes in 143 tissue samples, metallomes in 296 tissue samples, and three variomes covering 52 mouse inbred strains. All mouse multi-omics data can be explored through multiple functional modules with user-friendly web interface. Furthermore, we embedded several useful tools, like MISAweb, for the identification of microsatellite DNAs, and specifically developed the enrichment analysis modules of InterPro, Gene Ontology, and Pathway for mouse. The mouse multi-omics data can be downloaded online conveniently. MouseOmics will be updated regularly with the newly released mouse multi-omics data and can be accessed freely via the address https://www.varnatech.cn/MouseOmics.

