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Updated: Jan 14, 2026

Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse
Published on: October 6, 2023
Thyroid hormone and the brain
Daniel R Hochbaum1, Bernardo L Sabatini2
1Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
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Animals interact with their environment in a dynamic manner, with behavior shaped by a combination of internal state and external cues. Seasonal changes in food availability, for instance, alter food-seeking strategies, whereas progress through life stages drives changes in sexual behaviors and shifts in social hierarchies that can modulate dominance and aggression. In order to both mediate and adapt to these changes, animals coordinately modulate organ physiology and behavior. Much of this coordination is carried out by hormones - chemical messengers that are produced by one organ and travel through the bloodstream to affect other organs.
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