Improving completion of the red reflex examination at neonatal intensive care unit discharge: a practice improvement

Grant Shafer1,2, Kushal Bhakta3,2, Bheru Gandhi4,5

  • 1Neonatology, Children's Hospital of Orange County, Orange, California, USA grant.shafer@choc.org.

BMJ Open Quality
|October 21, 2025
PubMed

Insights

Improving the red reflex examination (RRE) in newborns is crucial. Quality improvement initiatives, including optimized ophthalmoscope placement and EHR reminders, achieved 100% RRE completion in NICUs.

Area of Science:

  • Neonatal care
  • Ophthalmology
  • Quality Improvement

Background:

  • The red reflex examination (RRE) is vital for detecting ophthalmologic abnormalities in newborns.
  • Low documentation rates of RRE completion were observed across multiple neonatal intensive care units (NICUs).

Purpose of the Study:

  • To implement and evaluate a quality improvement initiative to increase RRE completion rates before infant discharge.
  • To identify effective interventions for improving RRE documentation in NICUs.

Main Methods:

  • A driver diagram guided interventions at NICU 1, including clinician education and EHR reminders.
  • A 2^2 factorial planned experiment was conducted at three other NICUs, testing ophthalmoscope placement and EHR triggers.

Main Results:

  • Sustained RRE completion improved from 66.8% to 100% at NICU 1.
  • The combination of optimized ophthalmoscope placement and EHR RRE triggers achieved 100% compliance at all tested NICUs.

Conclusions:

  • Quality improvement efforts successfully enhanced RRE completion rates in a NICU setting.
  • A synergistic approach involving ophthalmoscope availability and EHR reminders shows promise for widespread RRE compliance.
Abstract

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