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Related Experiment Video

Updated: Jan 14, 2026

Automated Segmentation of Cortical Grey Matter from T1-Weighted MRI Images
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A lightweight network for brain MRI segmentation.

Pubali Chatterjee1, Amlan Chakrabarti2, Kaushik Das Sharma3

  • 1Department of Computer Science and Engineering, ITER, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, 751030, India. pubalichatterjee@soa.ac.in.

Scientific Reports
|October 21, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces a novel deep learning framework for accurate brain MRI segmentation. The lightweight model enhances disease identification and monitoring with superior performance and efficiency.

Keywords:
EfficientNet B0Hybrid loss functionImage segmentationLightweight networkMamba architectureVisual-State-Space block

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Neuroscience

Background:

  • Accurate brain Magnetic Resonance Imaging (MRI) segmentation is vital for diagnosing and tracking neurological conditions.
  • Existing deep learning models often struggle to balance high accuracy with computational efficiency for clinical applications.

Purpose of the Study:

  • To develop a novel, lightweight deep learning framework for precise brain MRI segmentation.
  • To improve the efficiency and accuracy of automated segmentation for clinical neuroimaging.

Main Methods:

  • Utilized EfficientNet B0 as an encoder for multi-scale feature extraction with reduced complexity.
  • Incorporated Visual State-Space blocks and multi-scale attention mechanisms for enhanced global context and feature refinement.
  • Employed a U-Net-inspired decoder with skip connections and a hybrid loss function (Active Contour Loss and Focal Loss) for robust training.

Main Results:

  • Achieved high segmentation accuracy with a computationally efficient, lightweight architecture.
  • Demonstrated superior segmentation performance compared to existing state-of-the-art methods.
  • Successfully segmented complex anatomical structures and lesions with precise boundary delineation.

Conclusions:

  • The proposed deep learning framework offers a promising solution for accurate and efficient brain MRI segmentation.
  • This approach facilitates improved disease identification and monitoring in clinical neuroimaging.
  • The lightweight design makes the model suitable for real-world deployment in medical settings.