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Modified inverted internal limiting membrane flap technique for lamellar macular hole
Khusbu Keyal1, Li Bing1, Liu Chunyu1
1Department of Ophthalmology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
BMC Ophthalmology
|October 22, 2025
Summary
This study demonstrates that pars plana vitrectomy with fovea sparing internal limiting membrane peeling and an inverted ILM flap effectively treats lamellar macular holes. The procedure shows good morphological and functional outcomes, improving visual acuity.
Area of Science:
- Ophthalmology
- Retinal Surgery
Background:
- Lamellar macular hole (LMH) is a partial-thickness macular defect.
- It is primarily caused by vitreofoveal traction and forces acting on the fovea.
Purpose of the Study:
- To evaluate the efficacy of a specific surgical technique for treating LMH.
- To assess the morphological and functional outcomes of the procedure.
Main Methods:
- Retrospective study of 19 eyes with LMH.
- Surgical technique involved 25-gauge pars plana vitrectomy (PPV), fovea sparing internal limiting membrane (ILM) peeling, and a modified inverted ILM flap under air.
Main Results:
- Improved foveal configuration in 78.94% of eyes.
- Mean best corrected visual acuity (BCVA) improved post-operatively.
- External limiting membrane (ELM) and ellipsoid zone (EZ) lines showed intactness in 68.42% of eyes post-surgery.
Conclusions:
- Pars plana vitrectomy (PPV) with fovea sparing ILM peeling and a modified inverted ILM flap under air yields favorable morphological and functional outcomes for LMH treatment.

