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Updated: Jan 14, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
A case of impending paradoxical embolism
Hideaki Kanda1, Kazuhisa Matsumoto2, Akira Hiwatashi2
1Department of Cardiovascular Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8520, Japan. h-kanda@m3.kufm.kagoshima-u.ac.jp.
Impending paradoxical embolism (IPDE) involves a clot in a patent foramen ovale. This case successfully removed the clot via cardiopulmonary bypass, preventing arterial embolism.
Area of Science:
- Cardiology
- Vascular Surgery
- Diagnostic Imaging
Background:
- Impending paradoxical embolism (IPDE) is a rare condition.
- Characterized by a thrombus within a patent foramen ovale (PFO).
- PFO allows venous thrombi to cross into the arterial circulation.
Purpose of the Study:
- To describe the successful management of a rare case of IPDE.
- To highlight the diagnostic utility of advanced imaging.
- To present a surgical approach to prevent arterial embolism.
Main Methods:
- Diagnosis of pulmonary embolism and IPDE using computed tomography and transesophageal echocardiography.
- Surgical removal of an incarcerated thrombus from the PFO.
- Closure of the PFO under cardiopulmonary bypass.
Main Results:
- A 24-year-old woman presented with chest pain and dyspnea.
- Transesophageal echocardiography confirmed a thrombus in the PFO.
- Successful surgical removal of the thrombus and PFO closure were performed.
Conclusions:
- Surgical intervention effectively treated IPDE in this patient.
- This approach prevented potential arterial thrombosis.
- Early diagnosis and intervention are crucial for managing IPDE.
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